DHRS4 antibody (AA 161-278) (Biotin)

Catalog No. ABIN1398151

This Rabbit Polyclonal antibody specifically detects DHRS4 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for DHRS4 antibody (AA 161-278) (Biotin) (ABIN1398151)

Target: DHRS4 (Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHRS4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-DHRS4 Antibody (Biotin)

Binding Specificity: AA 161-278

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHRS4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DHRS4

Target: DHRS4 (Dehydrogenase/reductase (SDR Family) Member 4 (DHRS4))

Alternative Name: DHRS4

Background:

Synonyms: NDRD, RRD, AI043103, AI790593, Carbonyl reductase, CR, D14Ucla2, Dehydrogenase/reductase SDR family member 4, Dhrs4, DHRS4_HUMAN, humNRDR antibody NADPH dependent carbonyl reductase/NADP retinol dehydrogenase, NADPH dependent retinol dehydrogenase/reductase, NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, NADPH-dependent retinol dehydrogenase/reductase, NRDR, Peroxisomal short chain alcohol dehydrogenase, Peroxisomal short-chain alcohol dehydrogenase, PHCR, PRO1800, PSCD, SCAD-SRL, SCADSRL, Short chain dehydrogenase/reductase family member 4, Short-chain dehydrogenase/reductase family member 4, UNQ851.

Background: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.Tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.

Gene ID: 10901