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UBR2 antibody (Ubiquitin Protein Ligase E3 Component N-Recognin 2) (Alexa Fluor 488) Primary Antibody

UBR2 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1401088
$476.30
Plus shipping costs $45.00
100 μL
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  • Target See all UBR2 Antibodies
    UBR2
    Reactivity
    • 46
    • 23
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 7
    • 4
    Rabbit
    Clonality
    • 44
    • 2
    Polyclonal
    Conjugate
    • 22
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBR2 antibody is conjugated to Alexa Fluor 488
    Application
    • 23
    • 20
    • 12
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UBR2
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    UBR2
    Alternative Name
    UBR2 (UBR2 Products)
    Synonyms
    ba49a4.1, si:ch211-239i4.2, C6orf133, RP3-392M17.3, bA49A4.1, dJ242G1.1, dJ392M17.3, 9930021A08Rik, AI462103, AW540746, E130209G04Rik, mKIAA0349, ubiquitin protein ligase E3 component n-recognin 2, ubiquitin protein ligase E3 component n-recognin 2 S homeolog, UBR2, ubr2, ubr2.S, Ubr2
    Background

    Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.

    Synonyms: E3 ubiquitin protein ligase UBR2, N recognin 2, Ubiquitin ligase E3 alpha II, Ubiquitin protein ligase E3 alpha 2, Ubiquitin protein ligase E3 component n recognin 2, UBR 2, UBR2_HUMAN, N-recognin-2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II.

    Gene ID
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