Astrotactin 2 antibody (AA 21-120) (Cy5)

Catalog No. ABIN1406992

This Rabbit Polyclonal antibody specifically detects Astrotactin 2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for Astrotactin 2 antibody (AA 21-120) (Cy5) (ABIN1406992)

Target: Astrotactin 2 (ASTN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Astrotactin 2 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Astrotactin 2 Antibody (Cy5)

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASTN2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Astrotactin 2

Target: Astrotactin 2 (ASTN2)

Alternative Name: ASTN2

Background:

Synonyms: Astn2, Astn-2, Astn 2, ASTN2_HUMAN, Astrotactin 2, Astrotactin2, Astrotactin-2, bA67K19.1, KIAA0634.

Background: Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.