Protocadherin 1 antibody (AA 51-150) (HRP)

Catalog No. ABIN1407230

The Rabbit Polyclonal anti-Protocadherin 1 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect Protocadherin 1 in samples from Human.

Quick Overview for Protocadherin 1 antibody (AA 51-150) (HRP) (ABIN1407230)

Target: Protocadherin 1 (PCDH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Protocadherin 1 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Protocadherin 1 Antibody (HRP)

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Protocadherin 1

Target: Protocadherin 1 (PCDH1)

Alternative Name: PCDH1

Background:

Synonyms: Cadherin like 1, Cadherin like protein 1, PC 42, PC42, PCDH 1, PCDH-1, PCDH 42, PCDH42, Protocadherin 1, Protocadherin 42, Protocadherin1, Protocadherin42.

Background: Protocadherins are a subfamily of cadherins, a large group of related glycoproteins that mediate calcium-dependent cell-to-cell adhesion via a homophilic mechanism. Involved in a variety of functions, protocadherins help to regulate neural development and synapse formation. PCDH1 is a 1,026 amino acid single-pass type I membrane protein that contains seven cadherin domains and is a member of the protocadherin family. Localized to cell-cell and cell-matrix boundaries and expressed at high levels in brain and neuro-glial cells, PCDH1 is thought to be involved in cell adhesion and cell-cell interactions and may play a role in neuronal development. PCDH1 contains a C-terminal cytoplasmic region, an extracellular region and a transmembrane region, and is expressed as two isoforms due to alternative splicing events.

Gene ID: 64121