DNAH9 antibody (AA 3001-3200) (HRP)

Catalog No. ABIN1407818

The Rabbit Polyclonal anti-DNAH9 antibody has been validated for ELISA, IHC (fro) and IHC (p). It is suitable to detect DNAH9 in samples from Human.

Quick Overview for DNAH9 antibody (AA 3001-3200) (HRP) (ABIN1407818)

Target: DNAH9 (Dynein, Axonemal, Heavy Chain 9 (DNAH9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAH9 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DNAH9 Antibody (HRP)

Binding Specificity: AA 3001-3200

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNAH9

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNAH9

Target: DNAH9 (Dynein, Axonemal, Heavy Chain 9 (DNAH9))

Alternative Name: DNAH9

Background:

Synonyms: Dynein heavy chain, Axonemal beta dynein heavy chain 9, Ciliary dynein heavy chain 9, Ciliary dynein heavy chain, DNAH 9, DNAH17L, DNAH9, DNAH9 variant protein, Dnahc 9, Dnahc9, DNAL 1, DNAL1, DNEL 1, DNEL1, DYH 9, DYH9, Dynein axonemal heavy chain 9, Dynein axonemal heavy polypeptide 17 like, Dynein axonemal heavy polypeptide 9, dynein heavy chain 9, axonemal, HL 20, HL20, KIAA0357, DYH9_HUMAN.

Background: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors, the complex transports cellular cargos towards the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH9 (Dynein, axonemal, heavy chain 9), also known as DYH9, HL20, DNEL1, Dnahc9 or DNAH17L, is a member of the Dynein heavy chain family and comprises one of the heavy chain subunits of axonemal Dynein. DNAH9 consists of an N-terminal stem which is responsible for interacting with other Dynein components and binding cargo, and four P-loops that comprise the motor domain at its C-terminus.