RSPH4A antibody (AA 435-482) (Cy3)

Catalog No. ABIN1409361

This anti-RSPH4A antibody is a Rabbit Polyclonal antibody detecting RSPH4A in WB, IF (cc) and IF (p). Suitable for Human and Mouse.

Quick Overview for RSPH4A antibody (AA 435-482) (Cy3) (ABIN1409361)

Target: RSPH4A (Radial Spoke Head 4 Homolog A (RSPH4A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPH4A antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RSPH4A Antibody (Cy3)

Binding Specificity: AA 435-482

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RSPH4A/RSHL3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RSPH4A

Target: RSPH4A (Radial Spoke Head 4 Homolog A (RSPH4A))

Alternative Name: RSPH4A/RSHL3

Background:

Synonyms: CILD11, dJ412I7.1, Radial spoke head protein 4 homolog A, Radial spoke head-like protein 3, RSH4A_HUMAN, RSHL3, Rsph4a, RSPH6B, A230081C05.

Background: RSHL3 is predicted to be a component of the radial spoke head based on homology with proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. RSHL3 (radial spoke head-like protein 3), also known as radial spoke head protein 4 homolog A, is a 716 amino acid protein that belongs to the flagellar radial spoke RSP4/6 family. Mutations in the RSHL3 gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Existing as three alternatively spliced isoforms, the RSHL3 gene contains 6 exons, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and P.falciparum, and maps to human chromosome 6q22.1.