PDE7B antibody (AA 281-360) (HRP)

Catalog No. ABIN1409984

The Rabbit Polyclonal anti-PDE7B antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect PDE7B in samples from Human, Mouse and Rat.

Quick Overview for PDE7B antibody (AA 281-360) (HRP) (ABIN1409984)

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE7B antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PDE7B Antibody (HRP)

Binding Specificity: AA 281-360

Specificity: Due to the sequence similarity, there is a chance that this antibody will recognize PDE7A, but the sequence is not continuous.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDE7B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDE7B

Target: PDE7B (phosphodiesterase 7B (PDE7B))

Alternative Name: PDE7B

Background:

Synonyms: bA472E5.1, cAMP-specific 3',5'-cyclic phosphodiesterase 7B, PDE7B

Background: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.

Gene ID: 27115

UniProt: Q9NP56

Pathways: cAMP Metabolic Process