WBP2 antibody (AA 1-100) (Cy5.5)

Catalog No. ABIN1410275

The Rabbit Polyclonal anti-WBP2 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect WBP2 in samples from Human.

Quick Overview for WBP2 antibody (AA 1-100) (Cy5.5) (ABIN1410275)

Target: WBP2 (WW Domain Binding Protein 2 (WBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WBP2 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-WBP2 Antibody (Cy5.5)

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WBP2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for WBP2

Target: WBP2 (WW Domain Binding Protein 2 (WBP2))

Alternative Name: WBP2

Background:

Synonyms: MGC18269, WBP 2, WBP-2, Wbp2, WBP2_HUMAN, WW domain binding protein 2, WW domain-binding protein 2.

Background: WW domain-binding protein 2 (WBP2) is a 261 amino acid protein expressed in most tissues. The WW domain is composed of 38 to 40 semi-conserved amino acids and is shared by various groups of proteins, including structural, regulatory and signaling proteins. The domain mediates protein-protein interactions through the binding of polyproline ligands. WBP2 binds to the WW domain of Yes-associated protein (YAP), WW domain containing E3 ubiquitin protein ligase 1 (AIP5) and WW domain containing E3 ubiquitin protein ligase 2 (AIP2). The gene encoding WBP2 is located on human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.