CALY antibody (AA 3-65) (HRP)

Catalog No. ABIN1410830

The Rabbit Polyclonal anti-CALY antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect CALY in samples from Human.

Quick Overview for CALY antibody (AA 3-65) (HRP) (ABIN1410830)

Target: CALY (Calcyon Neuron-Specific Vesicular Protein (CALY))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CALY antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CALY Antibody (HRP)

Binding Specificity: AA 3-65

Predicted Reactivity: Human,Mouse,Rat,Dog,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calcyon

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CALY

Target: CALY (Calcyon Neuron-Specific Vesicular Protein (CALY))

Alternative Name: Calcyon/Drd1ip

Background:

Synonyms: CALCYON, Caly, CALY_HUMAN, D1 dopamine receptor interacting protein, Drd1ip, Neuron specic vesicular protein calcyon, Neuron-specic vesicular protein calcyon, NSG3, RP11-122K13.5.

Background: Calcyon is a single transmembrane protein that interacts with D1 dopamine receptors. Dopamine is a neurotransmitter that regulates synaptic transmission involved in learning and memory. D1 receptors, the most abundant dopamine receptor in the central nervous system, appear to modulate the activity of D2 dopamine receptors, mediate various behavioural responses, and regulate neuron growth and differentiation. Calcyon is present in neuronal cell bodies and processes of the cortex and hippocampus, and it is especially abundant in pyramidal neurons. Interaction of Calcyon with D1 receptors results in a release of intracellular calcium.