ACBD3 antibody (AA 65-160) (Cy7)

Catalog No. ABIN1411944

This anti-ACBD3 antibody is a Rabbit Polyclonal antibody detecting ACBD3 in IF (cc) and IF (p). Suitable for Human.

Quick Overview for ACBD3 antibody (AA 65-160) (Cy7) (ABIN1411944)

Target: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACBD3 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ACBD3 Antibody (Cy7)

Binding Specificity: AA 65-160

Predicted Reactivity: Human,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACBD3/GOCAP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ACBD3

Target: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Alternative Name: ACBD3

Background:

Synonyms: ACBD 3, ACBD3, Acyl CoA binding domain containing protein 3, Acyl Coenzyme A binding domain containing 3, Acyl-CoA-binding domain-containing protein 3, GCP 60, GCP60, GCP60_HUMAN, GOCAP 1, GOCAP1, Golgi complex associated protein 1 60 kDa, Golgi complex associated protein 1, Golgi complex-associated protein 1, Golgi phosphoprotein 1, Golgi resident protein GCP60, GOLPH 1, GOLPH1, PAP 7, PAP7, PBR and PKA associated protein 7, PBR associated protein, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor associated protein PAP7, Peripheral benzodiazepine receptor-associated protein PAP7, Peripherial benzodiazepine receptor associated protein, PKA RIalpha associated protein.

Background: ACBD3 (acyl-CoA-binding domain-containing protein 3), also known as GCP60 (Golgi resident protein GCP60), GOCAP1, PAP7 or GOLPH1, is a Golgi apparatus membrane protein that contains one ACB (acyl-CoA-binding) domain and one GOLD (Golgi dynamics) domain which is essential for its interaction with other proteins. Expressed ubiquitously with highest expression in ovary and testis, ACBD3 is responsible for maintaining Golgi structure and, through binding to Giantin (golgin subfamily B member 1), functions to mediate protein transport between the Golgi and the endoplasmic reticulum (ER). Changes in the subcellular location of ACBD3 trigger signaling cascades within the Golgi that regulate cell fate and cell cycle progression. Additionally, ACBD3 is thought to act as a peripheral-type benzodiazepine receptor-associated protein, possibly playing a role in hormonal regulation and steroid formation.