HNRNPC antibody (AA 21-120) (Cy5)

Catalog No. ABIN1415285

The Rabbit Polyclonal anti-HNRNPC antibody has been validated for IF (cc) and IF (p). It is suitable to detect HNRNPC in samples from Rat.

Quick Overview for HNRNPC antibody (AA 21-120) (Cy5) (ABIN1415285)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HNRNPC Antibody (Cy5)

Binding Specificity: AA 21-120

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HNRPC

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HNRPC

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein C, Heterogeneous nuclear ribonucleoproteins C1/C2, HNRNP, hnRNP C1 / hnRNP C2, hnRNP C1/C2, hnRNPC, HNRPC, HNRPC_HUMAN, Nuclear ribonucleoprotein particle C1 protein, Nuclear ribonucleoprotein particle C2 protein, SNRPC.

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Gene ID: 3183