GLB1L3 antibody (AA 51-150) (Cy5.5)

Catalog No. ABIN1416787

This Rabbit Polyclonal antibody specifically detects GLB1L3 in WB, IF (cc), IF (p). It exhibits reactivity toward Mouse.

Quick Overview for GLB1L3 antibody (AA 51-150) (Cy5.5) (ABIN1416787)

Target: GLB1L3 (Galactosidase, beta 1-Like 3 (GLB1L3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLB1L3 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GLB1L3 Antibody (Cy5.5)

Binding Specificity: AA 51-150

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLB1L3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GLB1L3

Target: GLB1L3 (Galactosidase, beta 1-Like 3 (GLB1L3))

Alternative Name: GLB1L3

Background:

Synonyms: Beta galactosidase 1 like protein 3, Beta-galactosidase-1-like protein 3, FLJ90231, Galactosidase, beta 1 like 3, GLB1L 3, Glb1l3, GLBL3_HUMAN, LOC112937, OTTHUMP00000235427.

Background: GLB1L3 is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.