Hemoglobin Subunit beta antibody (Cy5.5)

Catalog No. ABIN1417561

This Rabbit Polyclonal antibody specifically detects Hemoglobin Subunit beta in WB. It exhibits reactivity toward Human.

Quick Overview for Hemoglobin Subunit beta antibody (Cy5.5) (ABIN1417561)

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hemoglobin Subunit beta antibody is conjugated to Cy5.5

Application: Western Blotting (WB)

Product Details anti-Hemoglobin Subunit beta Antibody (Cy5.5)

Specificity: Antibody has equal affinity for Human Hemoglobin Beta and Delta

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Hemoglobin beta

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Hemoglobin Subunit beta

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Alternative Name: Hemoglobin beta

Background:

Synonyms: CD113t-C, beta-globin, Hemoglobin subunit beta, Hemoglobin beta chain, HBB, Hemoglobin subunit delta, HBD, Delta-globin, Hemoglobin delta chain

Background: The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3 % of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.

Gene ID: 3043, 3045

UniProt: P68871, P02042