PDZD2 antibody (Cy5.5)

Catalog No. ABIN1418347

This Rabbit Polyclonal antibody specifically detects PDZD2 in IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDZD2 antibody (Cy5.5) (ABIN1418347)

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZD2 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PDZD2 Antibody (Cy5.5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDZK3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDZD2

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Alternative Name: PDZK3

Background:

Synonyms: Activated in prostate cancer protein, AIPC, KIAA0300, Likely ortholog of rat plakophilin related armadillo repeat protein interacting PDZ protein antibody PAPIN, PDZ domain containing 2, PDZ domain containing 3, PDZ domain containing protein 2, PDZ domain containing protein 3, PDZD2, PDZK 2, PDZK2, PDZK-2, PDZK 3, PDZK3, PDZK-3, PIN1, Plakophilin related armadillo repeat protein interacting PDZ protein like, Rat plakophilin related armadillo repeat protein interacting PDZ protein like, PDZD2_HUMAN.

Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Gene ID: 23037