ANKRD17 antibody (Cy5.5)

Catalog No. ABIN1419763

This Rabbit Polyclonal antibody specifically detects ANKRD17 in IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ANKRD17 antibody (Cy5.5) (ABIN1419763)

Target: ANKRD17 (Ankyrin Repeat Domain 17 (ANKRD17))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD17 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ANKRD17 Antibody (Cy5.5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD17

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANKRD17

Target: ANKRD17 (Ankyrin Repeat Domain 17 (ANKRD17))

Alternative Name: ANKRD17

Background:

Synonyms: ANKRD 17, ANKRD-17, Ankyrin repeat domain protein 17, Ankyrin repeat domain-containing protein 17, ANR17_HUMAN, FLJ22206, Gene trap ankyrin repeat, Gene trap ankyrin repeat protein, GTAR, KIAA0697, NY BR 16, Serologically defined breast cancer antigen NY-BR-16

Background: ANKRD17 is a 2,603 amino acid protein that contains 25 ankyrin repeats and one KH domain. ANKRD17 is expressed in bone marrow and is thought to be involved in liver development. ANKRD17 localizes to the cytoplasm and the nucleus. ANKRD17 exists as five alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 4. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.

Gene ID: 26057

Pathways: Regulation of Muscle Cell Differentiation