C2orf68 antibody (HRP)

Catalog No. ABIN1422670

This Rabbit Polyclonal antibody specifically detects C2orf68 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for C2orf68 antibody (HRP) (ABIN1422670)

Target: C2orf68 (Chromosome 2 Open Reading Frame 68 (C2orf68))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2orf68 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C2orf68 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf68

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C2orf68

Target: C2orf68 (Chromosome 2 Open Reading Frame 68 (C2orf68))

Alternative Name: C2orf68

Background:

Synonyms: Chromosome 2 open reading frame 68, FLJ14112, FLJ35653, MGC131675, CB068_HUMAN.

Background: C2orf68, also known as FLJ14112, FLJ35653 or MGC131675, is a 168 amino acid protein belonging to the UPF0561 family. Existing as two alternatively spliced isoforms, C2orf68 is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.