HEBP1 antibody (Cy5.5)

Catalog No. ABIN1423117

This Rabbit Polyclonal antibody specifically detects HEBP1 in WB and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HEBP1 antibody (Cy5.5) (ABIN1423117)

Target: HEBP1 (Heme Binding Protein 1 (HEBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEBP1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HEBP1 Antibody (Cy5.5)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HEBP1/p22HBP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HEBP1

Target: HEBP1 (Heme Binding Protein 1 (HEBP1))

Alternative Name: HEBP1

Background:

Synonyms: HBP, HEBP, Hebp1, HEBP1_HUMAN, Heme binding protein 1, Heme-binding protein 1, p22HBP.

Background: p22HBP, also known as HEBP1 (heme binding protein 1), HBP or HEBP, is a 189 amino acid intracellular tetrapyrrole-binding protein that assists in prevention of cellular toxicity by removing free porphyrinogens from the cell. Existing as a monomer, p22HBP localizes to cytoplasm and contains a 21 amino acid chemoattractant within its N-terminus that functions as a natural ligand for FPR3. p22HBP is a member of the HEBP family and binds N-methylprotoporphyrin and metalloporphyrins with similar affinity to porphyrinogens. The gene encoding p22HBP maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 50865