LRRTM2 antibody (PE-Cy5.5)

Catalog No. ABIN1428638

The Rabbit Polyclonal anti-LRRTM2 antibody has been validated for WB. It is suitable to detect LRRTM2 in samples from Human, Rat, Mouse, Cow, Dog, Pig.

Quick Overview for LRRTM2 antibody (PE-Cy5.5) (ABIN1428638)

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRTM2 antibody is conjugated to PE-Cy5.5

Application: Western Blotting (WB)

Product Details anti-LRRTM2 Antibody (PE-Cy5.5)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRTM2

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRRTM2

Target: LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))

Alternative Name: LRRTM2

Background:

Synonyms: KIAA0416, Leucine rich repeat transmembrane neuronal 2, Leucine rich repeat transmembrane neuronal 2 protein, Leucine rich repeat transmembrane protein 2, Leucine-rich repeat neuronal 2 protein, Leucine-rich repeat transmembrane neuronal protein 2, LRRN2, LRRT2_HUMAN, Lrrtm2.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM2 (leucine rich repeat transmembrane neuronal 2), also known as LRRN2, is a 516 amino acid single-pass type I membrane protein involved in the development maintenance of the vertebrate nervous system. Expressed in kidney and neuronal tissues, LRRTM2 contains ten LRR repeats and belongs to the LRRTM family. LRRTM2 is encoded by a gene that maps to human chromosome 5q31.2.

Molecular Weight: 55kDa

Pathways: Synaptic Membrane