P2RY10 antibody (PE-Cy5.5)

Catalog No. ABIN1429578

This anti-P2RY10 antibody is a Rabbit Polyclonal antibody detecting P2RY10 in WB and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for P2RY10 antibody (PE-Cy5.5) (ABIN1429578)

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY10 antibody is conjugated to PE-Cy5.5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-P2RY10 Antibody (PE-Cy5.5)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2Y10

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P2RY10

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Alternative Name: P2Y10

Background:

Synonyms: G protein coupled purinergic receptor P2Y10, P2ry10, P2Y like receptor, P2Y purinoceptor 10, P2Y-like receptor, P2Y10, P2Y10_HUMAN, Purinergic receptor P2Y G protein coupled 10, Putative P2Y purinoceptor 10.

Background: Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.

Molecular Weight: 39kDa

Gene ID: 27334

UniProt: O00398