GRID1 antibody (PE-Cy5)

Catalog No. ABIN1429702

This Rabbit Polyclonal antibody specifically detects GRID1 in FACS. It exhibits reactivity toward Human, Mouse, Rat, Chicken, Cow and Dog.

Quick Overview for GRID1 antibody (PE-Cy5) (ABIN1429702)

Target: GRID1 (Glutamate Receptor, Ionotropic, delta 1 (GRID1))

Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRID1 antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Product Details anti-GRID1 Antibody (PE-Cy5)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRID1

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GRID1

Target: GRID1 (Glutamate Receptor, Ionotropic, delta 1 (GRID1))

Alternative Name: GRID1

Background:

Synonyms: GluR delta 1, GluR delta 1 subunit, GluR delta-1 subunit, Glutamate receptor delta 1 subunit, Glutamate receptor delta-1 subunit, Glutamate receptor ionotropic delta 1, GRID 1, Grid1, GluD1, GRID1_HUMAN, KIAA1220.

Background: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder.

Molecular Weight: 110kDa

Gene ID: 2894

UniProt: Q9ULK0