KIR5.1 antibody (PE)

Catalog No. ABIN1430105

The Rabbit Polyclonal anti-KIR5.1 antibody has been validated for FACS. It is suitable to detect KIR5.1 in samples from Human, Rat and Mouse.

Quick Overview for KIR5.1 antibody (PE) (ABIN1430105)

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIR5.1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-KIR5.1 Antibody (PE)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KIR5.1

Isotype: IgG

Application Details

Application Notes: FCM: 1:20-100
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C

Expiry Date: 12 months

Target Details for KIR5.1

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Alternative Name: Kir5.1

Background:

The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.

Subcellular location: Extracellular

Synonyms: 6430410F18Rik, AI132396, BIR9, Inward rectier K channel Kir5.1, Inward rectier K+ channel Kir5.1, Inward rectier potassium channel 16, IRK16, IRKG, KCNJ16, MGC33717, Potassium channel inwardly rectying subfamily J member 16, Potassium inwardly rectying channel subfamily J member 16, RP23-218O16.1, IRK16_HUMAN.