LMBR1 antibody (PE-Cy7)

Catalog No. ABIN1436616

This anti-LMBR1 antibody is a Rabbit Polyclonal antibody detecting LMBR1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog and Pig.

Quick Overview for LMBR1 antibody (PE-Cy7) (ABIN1436616)

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMBR1 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-LMBR1 Antibody (PE-Cy7)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LMBR1/DIF14

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LMBR1

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Alternative Name: DIF14

Background:

Synonyms: ACHP, C7orf2, D 14, D14, Dferentiation related gene 14, Dferentiation related gene 14 protein, Dferentiation-related gene 14 protein, FLJ11665, Limb region 1 homolog mouse, Limb region 1 homolog, Limb region 1 protein, Limb region 1 protein homolog, LMBR 1, LMBR1, LMBR1_HUMAN, PPD 2, PPD2, TPT.

Background: LMBR1 is a 490 amino acid multi-pass membrane protein that is widely expressed with strongest expression in heart and pancreas. Belonging to the LIMR family, LMBR1 shares 95 % sequence identity with the mouse protein and may play crucial role in the evolution of limb and skeletal system. LMBR1 is critical for expression of sonic hedgehog (Shh) in the developing posterior limb bud mesenchyme. Mutations in the gene encoding LMBR1 is the cause of several rare conditions such as acheiropody (ACHP) and syndactyly type 4 (SDYT4). ACHP is an autosomal recessive inherited disorder characterized by bilateral congenital amputations of the hands and feet. LMBR1L (limb region 1 protein homolog-like), also known as LIMR (Lipocalin-1-interacting membrane receptor), is a 489 amino acid multi-pass membrane protein that is thought to act as a receptor for Lipocalin-1 and may also assist in its endocytosis.

Molecular Weight: 55kDa

Gene ID: 64327