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SBDS antibody (N-Term)

This anti-SBDS antibody is a Mouse Monoclonal antibody detecting SBDS in WB and EIA. Suitable for Human.
Catalog No. ABIN1449399

Quick Overview for SBDS antibody (N-Term) (ABIN1449399)

Target

See all SBDS Antibodies
SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reactivity

  • 35
  • 16
  • 16
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
Human

Host

  • 34
  • 1
Mouse

Clonality

  • 31
  • 4
Monoclonal

Conjugate

  • 18
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This SBDS antibody is un-conjugated

Application

  • 17
  • 10
  • 8
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone

AT1E8
  • Binding Specificity

    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-250, N-Term

    Cross-Reactivity (Details)

    Species reactivity (tested):Human.

    Purification

    Protein-G affinity chromatography

    Immunogen

    Recombinant human SBDS (1-250aa) purified from E. coli

    Isotype

    IgG2b
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL

    Buffer

    Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

    Alternative Name

    SBDS

    Background

    The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.Synonyms: Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein

    Gene ID

    51119

    NCBI Accession

    NP_057122

    UniProt

    Q9Y3A5

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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