AFF2 antibody (Middle Region)

Catalog No. ABIN1449867

The Rabbit Polyclonal anti-AFF2 antibody (ABIN1449867) specifically detects AFF2 in WB. The antibody is reactive with Human, Mouse, Cow and Chicken samples.

Quick Overview for AFF2 antibody (Middle Region) (ABIN1449867)

Target: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Reactivity: Human, Mouse, Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AFF2 Antibody

Binding Specificity: Middle Region

Sequence: AMGNCNNGPV TIPQRIHHMA ASHVNITSNV LRGYEHWDMA DKLTRENKEF

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Horse, Rabbit, Guinea PigSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human AFF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for AFF2

Target: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Alternative Name: AFF2 / FMR2

Background: AFF2 is a RNA-binding protein and might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. Defects in AFF2 are the cause of mental retardation X-linked associated with fragile site FRAXE (MRFRAXE). A form of mild to moderate mental retardation associated with learning difficulties, communication deficits, attention problems, hyperactivity, and autistic behavior. It is associated with a fragile site on chromosome Xq28.Synonyms: AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, Protein Ox19

Gene ID: 2334

NCBI Accession: NP_002016