BATF antibody (N-Term)

Catalog No. ABIN1449967

This Rabbit Polyclonal antibody specifically detects BATF in WB, IF and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BATF antibody (N-Term) (ABIN1449967)

Target: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BATF antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-BATF Antibody

Binding Specificity: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the amino terminus of Human BATF

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BATF

Target: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Alternative Name: BATF

Background: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.Synonyms: B-ATF, B-cell activating transcription factor, Basic leucine zipper transcriptional factor ATF-like, SF-HT-activated gene 2 protein, SFA-2, SFA2

Molecular Weight: 14 kDa

Gene ID: 10538

NCBI Accession: NP_006390