HIGD1A antibody (N-Term)

Catalog No. ABIN1450057

This Rabbit Polyclonal antibody specifically detects HIGD1A in WB, IF and EIA. It exhibits reactivity toward Human.

Quick Overview for HIGD1A antibody (N-Term) (ABIN1450057)

Target: HIGD1A (HIG1 Hypoxia Inducible Domain Family, Member 1A (HIGD1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIGD1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-HIGD1A Antibody

Binding Specificity: N-Term

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the amino terminus of Human HIG1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HIGD1A

Target: HIGD1A (HIG1 Hypoxia Inducible Domain Family, Member 1A (HIGD1A))

Alternative Name: HIG1

Background: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG1 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.Synonyms: HIGD1A, HSPC010, Hypoxia-inducible gene 1 protein, hypoxia inducible domain family 1A

Gene ID: 25994

NCBI Accession: NP_001093138