TMPRSS11A antibody (C-Term)
Quick Overview for TMPRSS11A antibody (C-Term) (ABIN1450094)
Target
See all TMPRSS11A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- TMPRSS11A (Transmembrane Protease, Serine 11A (TMPRSS11A))
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Alternative Name
- ECRG1
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Background
- Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.Synonyms: Airway trypsin-like protease 1, Esophageal cancer-susceptibility gene 1 protein, HATL1, HESP, TMPRSS11A
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Gene ID
- 339967
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UniProt
- Q6ZMR5
Target
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