This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target
PDZK1
(PDZ Domain Containing 1 (PDZK1))
Alternative Name
PDZD1
Background
PDZK1 is PDZ domain-containing scaffolding protein with a 519 amino acid protein. PDZK1 mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. This protein is expressed in the kidney, pancreas, liver, gastrointestinal tract, and adrenal cortex. In situ hybridization experiments showed that the expression of PDZK1 was limited to epithelial cells. In addition, PDZK1 was overexpressed in selected tumors of epithelial origin.Synonyms: CAP70, NHE-RF3, NHERF-3, NHERF3, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, NaPi-Cap1, PDZ domain-containing protein 1, PDZK1, Sodium-hydrogen exchanger regulatory factor 3