GFAP antibody (C-Term)

Catalog No. ABIN1512943

This Rabbit Polyclonal antibody specifically detects GFAP in WB, IHC and IF. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for GFAP antibody (C-Term) (ABIN1512943)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GFAP Antibody

Binding Specificity: C-Term

Sequence: RGTNESLERQ MREQEERHVR EAASYQEALA RLEEEGQSLK DEMARHLQEY QDLLNVKLAL DIEIATYRKL LEGEENRITI PVQTFSNLQI RETSLDTKSV SEGHLKRNIV VKTVEMRDGE VIKESKQEHK DVM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GFAP (NP_002046.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-GFAP antibody (ABIN1512943)

Qiang, Jun-Jie, Hai, Hong, Bing-Xi, Lei, Wei, Ya-Wei, Huang, Song-Tao, Yun-Tao: "TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling." in: Carcinogenesis, Vol. 39, Issue 2, pp. 214-224, (2018) (PubMed).

Yao, Weng, Zhang, Feng, Lin, Yao: "Interleukin-17A Acts to Maintain Neuropathic Pain Through Activation of CaMKII/CREB Signaling in Spinal Neurons." in: Molecular neurobiology, Vol. 53, Issue 6, pp. 3914-3926, (2016) (PubMed).

Target Details for GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Alternative Name: GFAP

Background: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,ALXDRD,GFAP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Astrocyte marker,Microglia marker,GFAP

Molecular Weight: 49 kDa/50 kDa

Gene ID: 2670

UniProt: P14136