FICD antibody

Catalog No. ABIN1526176

This Rabbit Polyclonal antibody specifically detects FICD in WB and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Dog and Cow.

Quick Overview for FICD antibody (ABIN1526176)

Target: FICD (FIC Domain Containing (FICD))

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FICD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FICD Antibody

Specificity: This antibody recognizes FICD.

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Canine (Dog), Horse, Human, Mouse, Rat, Guinea pig.
Species reactivity (tested):Human, Mouse, Rat, Bovine, Canine (Dog).

Purification: Affinity Chromatography

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a concentration of 1 mg/mL.

Concentration: 1.0 mg/mL

Target Details for FICD

Target: FICD (FIC Domain Containing (FICD))

Alternative Name: HIP13 / FICD

Background: FICD is an adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. It is able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.Synonyms: AMPylator FICD, Adenosine monophosphate-protein transferase FICD, FIC domain-containing protein, HYPE, Huntingtin yeast partner E, Huntingtin-interacting protein 13, Huntingtin-interacting protein E

Molecular Weight: 52 kDa (458 amino acids)

Gene ID: 11153