CCR5 antibody (pSer349)

Catalog No. ABIN1531218

This Rabbit Polyclonal antibody specifically detects CCR5 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CCR5 antibody (pSer349) (ABIN1531218)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCR5 Antibody

Binding Specificity: AA 303-352, pSer349

Specificity:

CCR5 (Phospho-Ser349) Antibody detects endogenous levels of CCR5 only when phosphorylated at Ser349.

PhosphorylationH:S349

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CCR5 around the phosphorylation site of Ser349.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:5000

Comment:

Unigene-Number: Hs.536735 (NCBI Gene Symbol: CCR5)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Alternative Name: CCR5

Background:

Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CD195 antigen, CHEMR13, CKR5, CMKBR5, HIV-1 fusion co-receptor, MIP-1 alpha receptor

NCBI Gene Symbol: CCR5

Molecular Weight: 40 kDa

Gene ID: 1234, 727797

OMIM: 601373

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size