PLCB3 antibody (pSer1105)

Catalog No. ABIN1531234

The Rabbit Polyclonal anti-PLCB3 antibody has been validated for WB, IHC and ELISA. It is suitable to detect PLCB3 in samples from Human, Rat and Mouse.

Quick Overview for PLCB3 antibody (pSer1105) (ABIN1531234)

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PLCB3 Antibody

Binding Specificity: AA 1071-1120, pSer1105

Specificity:

PLCB3 (Phospho-Ser1105) Antibody detects endogenous levels of PLCB3 only when phosphorylated at Ser1105.

PhosphorylationH:S1105 M:S1105 R:S1105

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PLCB3 around the phosphorylation site of Ser1105.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.591953 (NCBI Gene Symbol: PLCB3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PLCB3

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Alternative Name: PLCB3

Background:

Synonyms: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3, Phosphoinositide phospholipase C, Phospholipase C-beta-3, PLC-beta-3, PLCB3

NCBI Gene Symbol: PLCB3

Molecular Weight: 138 kDa

Gene ID: 5331

OMIM: 600230

UniProt: Q01970

Pathways: WNT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, CXCR4-mediated Signaling Events, G-protein mediated Events