INPP5D antibody (pTyr1021)

Catalog No. ABIN1531473

This anti-INPP5D antibody is a Rabbit Polyclonal antibody detecting INPP5D in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for INPP5D antibody (pTyr1021) (ABIN1531473)

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INPP5D antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-INPP5D Antibody

Binding Specificity: AA 987-1036, pTyr1021

Specificity:

SHIP1 (Phospho-Tyr1021) Antibody detects endogenous levels of SHIP1 only when phosphorylated at Tyr1021.

PhosphorylationH:Y1021 M:Y1020 R:Y1020

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SHIP1 around the phosphorylation site of Tyr1021.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:40000

Comment:

Unigene-Number: Hs.262886, Hs.601911 (NCBI Gene Symbol: INPP5D)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for INPP5D

Target: INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

Alternative Name: SHIP1

Background:

Synonyms: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1, Inositol polyphosphate-5-phosphatase of 145 kDaSIP-145, SH2 domain-containing inositol-5'-phosphatase 1, SH2 domain-containing inositol phosphatase 1, SHIP-1, p150Ship, hp51CN , INPP5D , SHIP, SHIP

NCBI Gene Symbol: INPP5D

Molecular Weight: 133 kDa

Gene ID: 3635

OMIM: 601582

UniProt: Q92835

Pathways: TCR Signaling, BCR Signaling, Warburg Effect