Calmodulin 1 antibody (pThr79)

Catalog No. ABIN1531529

The Rabbit Polyclonal anti-Calmodulin 1 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect Calmodulin 1 in samples from Human, Rat and Mouse. There is 1 publication available.

Quick Overview for Calmodulin 1 antibody (pThr79) (ABIN1531529)

Target: Calmodulin 1 (Calm1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmodulin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Calmodulin 1 Antibody

Binding Specificity: AA 46-95, pThr79

Specificity:

Calmodulin (Phospho-Thr79+Ser81) Antibody detects endogenous levels of Calmodulin only when phosphorylated at Thr79 and Ser81.

PhosphorylationH:T79+S81 M:T79+S81 R:T79+S81

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Calmodulin around the phosphorylation site of Thr79 and Ser81.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000

Comment:

Unigene-Number: Hs.282410, Hs.515487, Hs.643483, Hs.706125, Hs.708270, Hs.713288 (NCBI Gene Symbol: CALM1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

References for anti-Calmodulin 1 antibody (ABIN1531529)

Yokokura, Yurimoto, Matsuoka, Imataki, Dobashi, Bandoh, Matsunaga: "Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma." in: BMC cancer, Vol. 14, pp. 882, (2014) (PubMed).

Target Details for Calmodulin 1

Target: Calmodulin 1 (Calm1)

Alternative Name: Calmodulin

Background:

Synonyms: CALM, CALM1, CALM2, CALM3, CAM, CAM1, CAM2, CAM3, CAMB, CAMC

NCBI Gene Symbol: CALM1

Molecular Weight: 16 kDa

Gene ID: 801, 805, 808

OMIM: 114180

UniProt: P62158

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling