ATF4 antibody (pSer245)

Catalog No. ABIN1531779

This anti-ATF4 antibody is a Rabbit Polyclonal antibody detecting ATF4 in IHC and ELISA. Suitable for Human.

Quick Overview for ATF4 antibody (pSer245) (ABIN1531779)

Target: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-ATF4 Antibody

Binding Specificity: AA 212-261, pSer245

Specificity:

ATF4 (Phospho-Ser245) Antibody detects endogenous levels of ATF4 only when phosphorylated at Ser245.

PhosphorylationH:S245

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ATF4 around the phosphorylation site of Ser245.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.496487 (NCBI Gene Symbol: ATF4)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ATF4

Target: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Alternative Name: ATF4

Background:

Synonyms: activating transcription factor 4, ATF4, C/ATF, C/EBP-related ATF, CREB2, cyclic AMP response element-binding protein 2, cyclic-AMP-dependent transcription factor ATF-4, DNA-binding protein TAXREB67

NCBI Gene Symbol: ATF4

Molecular Weight: 38 kDa

Gene ID: 468

OMIM: 604064

UniProt: P18848

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response