MER/SKY (AA 716-765), (pTyr749) antibody

Catalog No. ABIN1532058

Product Details

Target: MER/SKY

Binding Specificity: AA 716-765, pTyr749

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Specificity:

MER/SKY (Phospho-Tyr749/681) Antibody detects endogenous levels of MER/SKY only when phosphorylated at Tyr749/681.

PhosphorylationH:Y749/681 M:Y744/671 R:Y744/671

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MER/SKY around the phosphorylation site of Tyr749/681.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.306178, Hs.677398, Hs.381282 (NCBI Gene Symbol: MERTK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details

Target: MER/SKY

Background:

Synonyms: C-mer, Receptor tyrosine kinase MerTK/ Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase DTK, Protein-tyrosine kinase byk

NCBI Gene Symbol: MERTK

Molecular Weight: 110 kDa

Gene ID: 10461, 7301

OMIM: 268000

UniProt: Q12866, Q06418