Aggrecan antibody (Cleaved-Asp369)
Quick Overview for Aggrecan antibody (Cleaved-Asp369) (ABIN1536077)
Target
See all Aggrecan (ACAN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 320-369, Cleaved-Asp369
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Specificity
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Aggrecan (Cleaved-Asp369) Antibody detects endogenous levels of fragment of activated Aggrecan resulting from cleavage adjacent to Asp369.
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Aggrecan.
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Isotype
- IgG
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Application Notes
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
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Comment
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Unigene-Number: Hs.2159, Hs.616395 (NCBI Gene Symbol: ACAN)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable at -20°C for at least 1 year.
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Expiry Date
- 12 months
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- Aggrecan (ACAN)
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Alternative Name
- Aggrecan
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Background
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Synonyms: aggrecan core protein, cartilage-specific proteoglycan core protein, chondroitin sulfate proteoglycan core protein 1, CSPCP, CSPG1, PGCA, PGCA
NCBI Gene Symbol: ACAN
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Molecular Weight
- 44 kDa
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Gene ID
- 176
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OMIM
- 155760
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UniProt
- P16112
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Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
Target
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