Kallikrein 2 antibody (C-Term)

Catalog No. ABIN1536788

The Rabbit Polyclonal anti-Kallikrein 2 antibody has been validated for WB. It is suitable to detect Kallikrein 2 in samples from Human. There is 1 publication available.

Quick Overview for Kallikrein 2 antibody (C-Term) (ABIN1536788)

Target: Kallikrein 2 (KLK2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB06101

Product Details anti-Kallikrein 2 Antibody

Binding Specificity: AA 166-197, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Kallikrein 2 (KLK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Kallikrein 2 antibody (ABIN1536788)

Guihard, Yao, Blazquez-Medela, Iruela-Arispe, Boström, Yao: "Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167936, (2017) (PubMed).

Target Details for Kallikrein 2

Target: Kallikrein 2 (KLK2)

Background: Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2, encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.

Molecular Weight: 28671

Gene ID: 3817

NCBI Accession: NP_001002231, NP_001243009, NP_005542

UniProt: P20151

Pathways: Complement System