KHDRBS1 antibody (C-Term)

Catalog No. ABIN1537301

The Rabbit Polyclonal anti-KHDRBS1 antibody has been validated for WB. It is suitable to detect KHDRBS1 in samples from Mouse. There is 1 publication available.

Quick Overview for KHDRBS1 antibody (C-Term) (ABIN1537301)

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHDRBS1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40286

Product Details anti-KHDRBS1 Antibody

Binding Specificity: AA 414-443, C-Term

Predicted Reactivity: C, H, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Mouse Khdrbs1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-KHDRBS1 antibody (ABIN1537301)

Zhang, Yu, Li, Jiang, Zhou: "Utility of SAM68 in the progression and prognosis for bladder cancer." in: BMC cancer, Vol. 15, pp. 364, (2015) (PubMed).

Target Details for KHDRBS1

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Alternative Name: Khdrbs1

Background: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

Molecular Weight: 48371

Gene ID: 20218

NCBI Accession: NP_035447

UniProt: Q60749

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy