CD68 antibody (AA 209-237)

Catalog No. ABIN1538079

This anti-CD68 antibody is a Rabbit Polyclonal antibody detecting CD68 in WB. Suitable for Human.

Quick Overview for CD68 antibody (AA 209-237) (ABIN1538079)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB36354

Product Details anti-CD68 Antibody

Binding Specificity: AA 209-237

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CD68/CD68 (kpi) Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68/CD68

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Molecular Weight: 37408

Gene ID: 968

NCBI Accession: NP_001035148, NP_001242

UniProt: P34810