MYH7 antibody (N-Term)

Catalog No. ABIN1539139

This Rabbit Polyclonal antibody specifically detects MYH7 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for MYH7 antibody (N-Term) (ABIN1539139)

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYH7 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB37906

Product Details anti-MYH7 Antibody

Binding Specificity: AA 185-211, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the N-terminal region of human MYH7.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MYH7 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Alternative Name: MYH7

Background: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Molecular Weight: 223097

Gene ID: 4625

NCBI Accession: NP_000248

UniProt: P12883