MBP antibody

Catalog No. ABIN1539854

The Mouse Monoclonal anti-MBP antibody has been validated for WB and IF. It is suitable to detect MBP in samples from Human.

Quick Overview for MBP antibody (ABIN1539854)

Target: MBP

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MBP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 408CT17-4-3

Product Details anti-MBP Antibody

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: Purified His-tagged MBP protein(Fragment) was used to produced this monoclonal antibody.

Isotype: IgM

Application Details

Application Notes: IF: 1:10~50. WB: 1:5000~16000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MBP Antibody (Ascites) can be refrigerated at 2-8Â °C for up to 6 months. For long term storage, keep at -20Â °C.

Expiry Date: 6 months

Target Details for MBP

Target: MBP

Background: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq].

Molecular Weight: 33117

Gene ID: 4155

NCBI Accession: NP_001020252, NP_001020261, NP_001020263, NP_001020271, NP_001020272, NP_002376

UniProt: P02686