HMGB2 antibody (AA 64-92)

Catalog No. ABIN1539937

Product Details anti-HMGB2 Antibody

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Binding Specificity: AA 64-92

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HMGB2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.

Clone: 523ct16-1-1

Isotype: IgG2b

Application Details

Application Notes: WB: 1:500~8000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HMG2 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Alternative Name: HMG2 (HMGB2 Products)

Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 11832

Gene ID: 8091

NCBI Accession: NP_003474, NP_003475

UniProt: P52926

Pathways: Cellular Response to Molecule of Bacterial Origin