FOXP2 antibody (AA 657-684)

Catalog No. ABIN1539974

The Mouse Monoclonal anti-FOXP2 antibody has been validated for WB. It is suitable to detect FOXP2 in samples from Human.

Quick Overview for FOXP2 antibody (AA 657-684) (ABIN1539974)

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 533CT26-1-2

Product Details anti-FOXP2 Antibody

Binding Specificity: AA 657-684

Predicted Reactivity: M, Rat

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This FOXP2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 657-684 amino acids from human FOXP2.

Isotype: IgM

Application Details

Application Notes: WB: 1:100~1600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FOXP2 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Alternative Name: FOXP2

Background: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Molecular Weight: 79919

Gene ID: 93986

NCBI Accession: NP_001166237, NP_001166238, NP_055306, NP_683696, NP_683697, NP_683698

UniProt: O15409