CD33 antibody (AA 337-364)

Catalog No. ABIN1540002

This anti-CD33 antibody is a Mouse Monoclonal antibody detecting CD33 in WB and IF. Suitable for Human.

Quick Overview for CD33 antibody (AA 337-364) (ABIN1540002)

Target: CD33

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD33 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 574CT16-4-4

Product Details anti-CD33 Antibody

Binding Specificity: AA 337-364

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This CD33 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-364 amino acids from human CD33.

Isotype: IgM

Application Details

Application Notes: IF: 1:10~50. WB: 1:100~500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CD33 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CD33

Target: CD33

Alternative Name: CD33

Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Molecular Weight: 39825

Gene ID: 945

NCBI Accession: NP_001076087, NP_001171079, NP_001763

UniProt: P20138