FAF1 antibody

Catalog No. ABIN155080

This Rabbit Polyclonal antibody specifically detects FAF1 in WB, IHC (p) and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FAF1 antibody (ABIN155080)

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-FAF1 Antibody

Specificity: This antibody detects FAF1.

Purification: Affinity purified

Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 640 of human FAF1

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL, Rat kidney cell lysate can be used as a positive control. Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAF1

Background: FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TRADD, FADD, and RIP, FAF1 lacks a DDH (Death domain homologous region) and cannot induce apoptosis independent of Fas activation.Synonyms: CGI-03, FAS-associated factor 1, UBX domain-containing protein 12, UBX domain-containing protein 3A, UBXD12, UBXN3A

Gene ID: 11124

NCBI Accession: NP_008982

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location