CEBPB antibody (AA 1-271)

Catalog No. ABIN165382

Product Details anti-CEBPB Antibody

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Binding Specificity: AA 1-271

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human C/EBP-beta (1-271 aa) purified from E. coli

Clone: 47A1

Isotype: IgG1 kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: CEBP beta/CEBPB (CEBPB Products)

Background: CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPalpha, C/EBPbeta, C/EBPdelta, C/EBPepsilon, and C/EBPgamma. Among these proteins, C/EBPbeta is usually highly expressed in liver, intestine, lung and adipose. C/EBPbeta has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated.

NCBI Accession: NP_005185

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation