PSPH antibody (AA 1-225)

Catalog No. ABIN165446

Product Details anti-PSPH Antibody

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Binding Specificity: AA 1-225

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSPH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human PSP (1-225aa) purified from E. coli

Clone: 3G12

Isotype: IgG1 kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for PSPH

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Alternative Name: Phosphoserine phosphatase/PSPH (PSPH Products)

Background: Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg (2+) -dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.

NCBI Accession: NP_004568

Pathways: Warburg Effect