ABCG1 antibody (AA 1-220)

Catalog No. ABIN1678514

The Rabbit Polyclonal anti-ABCG1 antibody has been validated for WB, IHC and IF. It is suitable to detect ABCG1 in samples from Human. There is 1 publication available.

Quick Overview for ABCG1 antibody (AA 1-220) (ABIN1678514)

Target: ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ABCG1 Antibody

Binding Specificity: AA 1-220

Sequence: MACLMAAFSV GTAMNASSYS AEMTEPKSVC VSVDEVVSSN MEATETDLLN GHLKKVDNNL TEAQRFSSLP RRAAVNIEFR DLSYSVPEGP WWRKKGYKTL LKGISGKFNS GELVAIMGPS GAGKSTLMNI LAGYRETGMK GAVLINGLPR DLRCFRKVSC YIMQDDMLLP HLTVQEAMMV SAHLKLQEKD EGRREMVKEI LTALGLLSCA NTRTGSLSGG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ABCG1 (NP_058198.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-ABCG1 antibody (ABIN1678514)

He, Zhang, Pang, Yu, Xiong, Zhu, Chen: "SIRT6 reduces macrophage foam cell formation by inducing autophagy and cholesterol efflux under ox-LDL condition." in: The FEBS journal, Vol. 284, Issue 9, pp. 1324-1337, (2017) (PubMed).

Target Details for ABCG1

Target: ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))

Alternative Name: ABCG1

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.,ABC8,WHITE1,ABCG1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Cell Type Marker,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,Astrocyte marker,ABCG1

Molecular Weight: 71 kDa/73 kDa/74 kDa/75 kDa/86 kDa

Gene ID: 9619

UniProt: P45844

Pathways: Lipid Metabolism