CNR1 antibody (AA 1-120)
Quick Overview for CNR1 antibody (AA 1-120) (ABIN1679303)
Target
See all CNR1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-120
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Sequence
- MKSILDGLAD TTFRTITTDL LYVGSNDIQY EDIKGDMASK LGYFPQKFPL TSFRGSPFQE KMTAGDNPQL VPADQVNITE FYNKSLSSFK ENEENIQCGE NFMDIECFMV LNPSQQLAIA
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CNR1 (NP_001153731.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CNR1 (Cannabinoid Receptor 1 (CNR1))
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Alternative Name
- CNR1
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Background
- This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.,CNR1,CANN6,CB-R,CB1,CB1A,CB1K5,CB1R,CNR,Cancer,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,CNR1
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Molecular Weight
- 45 kDa/49 kDa/52 kDa
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Gene ID
- 1268
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UniProt
- P21554
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Pathways
- Feeding Behaviour
Target
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